Follicular growth: the basic event in the mouse and human ovary.

Effect of lysophosphatidic acid on the follicular development and the ‎expression of lysophosphatidic acid receptor genes during in vitro culture of ‎mouse ovary

Lysophosphatidic acid (LPA) known as a serum-derived growth factor, is involved in several cell physiological functions in the female reproductive system including: oocyte maturation, in vitro fertilization and embryo implantation by its transmembrane G protein-coupled receptors. The aim of the present study was to examine the effect of LPA on in vitro follicular development o...

P-46: Proliferative Activity of Follicular Cells in Adult Mouse Ovary Following Administration of Exogenous Nicotine

Background: Nicotine can induce sub fertility and infertility in females. The aim of this study was to determine the effect of nicotine on follicular cells proliferative activity in mouse ovary. Materials and Methods: Female adult NMRI mice were divided into two groups. Animals in control group received vehicle, however in experimental group, animals were treated with 0.4mg/kg of nicotine for 1...

P-170: Animal Models of Human Artificial Ovary, Valuable Tools for Fertility Preservation in Cancer Patients

Background: With all the recent advances in cancer treatments, many young cancer patients find themselves facing the prospect of losing their fertility after aggressive chemotherapy or radiotherapy. Cryopreservation of ovarian cortical tissue has emerged as a potential option to restore fertility in these young women. Materials and Methods: Because autotransplantation of cryopreserved ovarian c...

Steroid Production and Follicular Development of Neonatal Mouse Ovary during In Vitro Culture

P-217: The Effect of Progesterone on The In Vitro Maturation of Mouse Germinal Vesicle Oocytes Derived from Polycystic Ovary

Background: Polycystic ovary syndrome (PCOS) is characterized by chronic anovulation and hyperandro genism and affects approximately 5-10% of women of reproductive age. In vitro maturation (IVM) of mammalian oocytes has become an efficient method to produce mature oocytes in order to use in assisted reproductive techniques such as in vitro fertilization (IVF), intra cytoplasmic sperm injection ...